Funded Research Outcomes

Papers Published on Foundation Funded Projects - 2014




Economic evaluation of decompressive craniectomy versus barbiturate coma for refractory intracranial hypertension following traumatic brain injury

Alali, A.S.
Nathens, A.B.
Scales, D.C.

Crit Care Med. 2014 Oct;42(10):2235-43

Beta blockers for acute traumatic brain injury: a systematic review and meta-analysis

Alali, A.S.
Nathens, A.B.

Neurocrit Care. 2014 Jun;20(3):514-23

Beta blockers for acute traumatic brain injury: a systematic review and meta-analysis

Alali, A.S.
Nathens, A.B.

Neurocrit Care. 2014 Jun;20(3):514-23

Tracheostomy timing in traumatic brain injury: a propensity-matched cohort study

Alali, A.S.
Nathens, A.B.

J Trauma Acute Care Surg. 2014 Jan; 76(1):70-6; discussion 76-8

Intracranial pressure monitoring in severe traumatic brain injury: results from the American College of Surgeons Trauma Quality Improvement Program

Alali, A.S.
Nathens, A.B.
Scales, D.C.

J Neurotrauma. 2013 Oct 15;30(20):1737-46

Reconstruction of the coronoid process using the tip of the ipsilateral olecranon

Alolabi, B.
King, G.J.W.

J Bone Joint Surg Am. 2014 Apr 2;96(7):590-6

Hippocampal malrotation is associated with chromosome 22q11.2 microdeletion

Andrade, D.M.

Can J Neurol Sci. 2013 Sep;40(5):652-6

Improved procedural performance following a simulation training session may not be transferable to the clinical environment

Bismilla, Z.
Whyte, H.E.

J Perinatol. 2012 Jul;32(7):539-44

High-fidelity simulator technology may not be superior to traditional low-fidelity equipment for neonatal resuscitation training

Bismilla, Z.
Whyte, H.E.

J Perinatol. 2012 Apr;32(4):287-92

Impact of nasal surgery on speech resonance

Brandt, M.G.
Rotenberg, B.W.

Ann Otol Rhinol Laryngol. 2014 Aug; 123(8):564-70

The addition of epidural local anesthetic to systemic multimodal analgesia following lumbar spinal fusion: a randomized controlled trial

Choi, S.
Brull, R.

Anesthesiology. 2014 Feb;120(2):299-311

Postoperative changes in sleep-disordered breathing and sleep architecture in patients with obstructive sleep apnea

Chung, F.
Shapiro, C.M.

Anesthesiology. 2014 Feb;120(2):287-98

Predictive performance of the STOP-Bang score for identifying obstructive sleep apnea in obese patients

Chung, F.

Obes Surg. 2013 Dec;23(12):2050-7

Serum bicarbonate level improves specificity of STOP-Bang screening for obstructive sleep apnea

Chung, F.
Shapiro, C.M.

Chest. 2013 May;143(5):1284-93

Proportion of surgical patients with undiagnosed obstructive sleep apnoea

Chung, F.
Shapiro, C.M.

Br J Anaesth. 2013 Apr;110(4):629-36

Obstructive sleep apnea and oxygen therapy: a systematic review of the literature and meta-analysis

Chung, F.

J Clin Sleep Med. 2013 Mar 15;9(3):271-9

Development, implementation, and dissemination of the I-PASS handoff curriculum: a multisite educational intervention to improve patient handoffs

Coffey, M.

Acad Med. 2014 Jun;89(6):876-84

An anthropometric study of the distal humerus

Desai, S.J.
King, G.J.W.

J Shoulder Elbow Surg. 2014 Apr;23(4):463-9

Hemiarthroplasty of the elbow: the effect of implant size on kinematics and stability

Desai, S.J.
King, G.J.W.

J Shoulder Elbow Surg. 2014 Jul;23(7):946-54

Vital signs after cardiac arrest following withdrawal of life-sustaining therapy: a multicenter prospective observational study

Dhanani, S.

Crit Care Med. 2014 Nov;42(11):2358-69

Mechanical ventilation triggers hippocampal apoptosis by vagal and dopaminergic pathways

dos Santos, C.C.

Am J Respir Crit Care Med. 2013 Sep 15;188(6):693-702

Network analysis of transcriptional responses induced by mesenchymal stem cell treatment of experimental sepsis

dos Santos, C.C.

Am J Pathol. 2012 Nov;181(5):1681-92

Identification of patient-derived outcomes after aortic aneurysm repair

Dubois, L.
Forbes, T.L.

J Vasc Surg. 2014 Jun;59(6):1528-34

Assessment and treatment of post patent ductus arteriosus ligation syndrome

El-Khuffash, A.F.
McNamara, P.J.

J Pediatr. 2014 Jul;165(1):46-52.e1

Multidisciplinary consensus on assessment of unruptured intracranial aneurysms: proposal of an international research group

Etminan, N.

Stroke. 2014 May;45(5):1523-30

Age of collagen in intracranial saccular aneurysms

Etminan, N.

Stroke. 2014 Jun;45(6):1757-63

A spatial analysis of private well water Escherichia coli contamination in southern Ontario

Evans, G.

Geospat Health. 2013 Nov;8(1):65-75

Intravenous magnesium sulfate for vaso-occlusive episodes in sickle cell disease

Friedman, J.N.
Goldman, R.D.

Pediatrics. 2013 Dec;132(6):e1634-41

The combined effect of maternal obesity and fetal macrosomia on pregnancy outcomes

Gaudet, L.
Walker, M.

J Obstet Gynaecol Can. 2014 Sep;36(9):776-84

Obstructive sleep apnea and the prevalence and incidence of cancer

Gershon, A.S.

CMAJ. 2014 Sep 16;186(13):985-92

Quantifying comorbidity in individuals with COPD: a population study

Gershon, A.S.

Eur Respir J. 2015 Jan;45(1):51-9

Obstructive sleep apnea and incident diabetes. A historical cohort study

Gershon, A.S.

Am J Respir Crit Care Med. 2014 Jul 15;190(2):218-25

The effect of triple vs. double nonopioid therapy on postoperative pain and functional outcome after abdominal hysterectomy: a randomised control trial

Gilron, I.

Eur J Anaesthesiol. 2014 Dec 5. [Epub ahead of print]

Antidepressant drugs for prevention of acute and chronic postsurgical pain: early evidence and recommended future directions

Gilron, I.

Anesthesiology. 2014 Sep;121(3):591-608

Prevention of chronic pain after surgery: new insights for future research and patient care

Gilron, I.

Can J Anaesth. 2014 Feb;61(2):101-11

Combination pharmacotherapy for management of chronic pain: from bench to bedside

Gilron, I.

Lancet Neurol. 2013 Nov;12(11):1084-95

Breathing helium-hyperoxia and tolerance of partitioned exercise in patients with COPD

Goldstein, R.S.

J Cardiopulm Rehabil Prev. 2014 Jan-Feb;34(1):69-74

Continuous electroencephalography for seizures and status epilepticus

Hahn, C.D.

Curr Opin Pediatr. 2014 Dec;26(6):675-81

Seizure burden is independently associated with short term outcome in critically ill children

Hahn, C.D.

Brain. 2014 May;137(Pt 5):1429-38

Neurocritical care: seizures after acute brain injury-more than meets the eye

Hahn, C.D.

Nat Rev Neurol. 2013 Dec;9(12):662-4

Electroencephalography monitoring in critically ill children: current practice and implications for future study design

Hahn, C.D.

Epilepsia. 2013 Aug;54(8):1419-27

Electrographic seizures in pediatric ICU patients: cohort study of risk factors and mortality

Hahn, C.D.

Neurology. 2013 Jul 23;81(4):383-91

Double-chamber rotating bioreactor for dynamic perfusion cell seeding of large-segment tracheal allografts: comparison to conventional static methods

Haykal, S.
Waddell, T.K.

Tissue Eng Part C Methods. 2014 Aug;20(8):681-92

The effect of decellularization of tracheal allografts on leukocyte infiltration and of recellularization on regulatory T cell recruitment

Haykal, S.
Waddell, T.K.

Biomaterials. 2013 Jul;34(23):5821-32

Evaluation of the structural integrity and extracellular matrix components of tracheal allografts following cyclical decellularization techniques: comparison of three protocols

Haykal, S.
Waddell, T.K.

Tissue Eng Part C Methods. 2012 Aug;18(8):614-23

Pathway-based analysis of primary biliary cirrhosis genome-wide association studies

Hirschfield, G.M.
Siminovitch, K.A.

Genes Immun. 2013 Apr;14(3):179-86

Immunochip analyses identify a novel risk locus for primary biliary cirrhosis at 13q14, multiple independent associations at four established risk loci and epistasis between 1p31 and 7q32 risk variants

Hirschfield, G.M.
Siminovitch, K.A.

Hum Mol Genet. 2012 Dec 1;21(23):5209-21

Association of primary biliary cirrhosis with variants in the CLEC16A, SOCS1, SPIB and SIAE immunomodulatory genes

Hirschfield, G.M.
Siminovitch, K.A.

Genes Immun. 2012 Jun;13(4):328-35

Abnormal trigeminal nerve microstructure and brain white matter in idiopathic trigeminal neuralgia

Hodaie, M.
Davis, K.D.

Pain. 2014 Jan; 155(1):37-44

Accidental falls and risk of mortality among older adults on chronic peritoneal dialysis

Jassal, S.V.

Clin J Am Soc Nephrol. 2014 Jul;9(7):1248-53

Functional disability in older adults maintained on peritoneal dialysis therapy

Jassal, S.V.

Perit Dial Int. 2014 Apr 7. [Epub ahead of print]

Leukocyte infiltration and activation of the NLRP3 inflammasome in white adipose tissue following thermal injury

Jeschke, M.G.

Crit Care Med. 2014 Jun;42(6):1357-64

Ex vivo expansion of hematopoietic stem and progenitor cells: recent advances

Jeschke, M.G.

World J Hematol 2014 May 6; 3(2): 18-28

Hypoglycemia is associated with increased postburn morbidity and mortality in pediatric patients

Jeschke, M.G.

Crit Care Med. 2014 May;42(5):1221-31

Survivors versus nonsurvivors postburn: differences in inflammatory and hypermetabolic trajectories

Jeschke, M.G.

Ann Surg. 2014 Apr;259(4):814-23

Burn plus lipopolysaccharide augments endoplasmic reticulum stress and NLRP3 inflammasome activation and reduces PGC-1α in liver

Jeschke, M.G.

Shock. 2014 Feb;41(2):138-44

The use of dermal substitutes in burn surgery: acute phase

Jeschke, M.G.

Wound Repair Regen. 2014 Jan;22(1):14-22

Prenatal anti-Ro antibody exposure, congenital complete atrioventricular heart block, and high-dose steroid therapy: impact on neurocognitive outcome in school-age children

Kelly, E.N.
Sananes, R.

Arthritis Rheumatol. 2014 Aug;66(8):2290-6

Drug use prior to incarceration and associated socio-behavioural factors among males in a provincial correctional facility in Ontario, Canada

Kouyoumdjian, F.G.
Main, C.

Can J Public Health. 2014 May 9; 105(3):e198-202

Impact of clopidogrel plus aspirin versus aspirin alone on the progression of native coronary artery disease after bypass surgery: analysis from the Clopidogrel After Surgery for Coronary Artery DiseasE (CASCADE) randomized trial

Kulik, A.
Ruel, M.

Circulation. 2014 Sep 9;130(11 Suppl 1):S12-8

Cardiopulmonary fitness correlates with regional cerebral grey matter perfusion and density in men with coronary artery disease

Lanctôt, K.L.
Herrmann, N.

PLoS One. 2014 Mar 12;9(3):e91251

Assessing cognitive effects of anticholinergic medications in patients with coronary artery disease

Lanctôt, K.L.
Herrmann, N.

Psychosomatics. 2014 Jan-Feb;55(1):61-8

Ceramides predict verbal memory performance in coronary artery disease patients undertaking exercise: a prospective cohort pilot study

Lanctôt, K.L.
Herrmann, N.

BMC Geriatr. 2013 Dec 12;13(1):135

Higher cortisol predicts less improvement in verbal memory performance after cardiac rehabilitation in patients with coronary artery disease

Lanctôt, K.L.
Herrmann, N.

Cardiovasc Psychiatry Neurol. 2013; 2013:340342

Targeted temperature management processes and outcomes after out-of-hospital cardiac arrest: an observational cohort study

Lin, S.
Morrison, L.J.
Scales, D.C.

Crit Care Med. 2014 Dec;42(12):2565-74

External rotation immobilization for primary shoulder dislocation: a randomized controlled trial

Litchfield, R.
Whelan, D.B.

Clin Orthop Relat Res. 2014 Aug;472(8):2380-6

Carbon monoxide releasing molecules inhibit cell death resulting from renal transplantation related stress

Luke, P.P.

J Urol. 2013 Aug;190(2):772-8

VPAC2 receptor agonist BAY 55-9837 increases SMN protein levels and moderates disease phenotype in severe spinal muscular atrophy mouse models

MacKenzie, A.

Orphanet J Rare Dis. 2014 Jan 9;9(1):4

The liver in sepsis: shedding light on the cellular basis of hepatocyte dysfunction

Marshall, J.C.

Crit Care. 2013 Jun 12;17(3):153

Subjective memory evaluation before and after temporal lobe epilepsy surgery

McLachlan, R.S.

PLoS One. 2014 Apr 1;9(4):e93382

Maternal, umbilical arterial and umbilical venous 25-hydroxyvitamin D and adipocytokine concentrations in pregnancies with and without gestational diabetes

McManus, R.
de Vrijer, B.

Clin Endocrinol (Oxf). 2014 May;80(5):635-41

Analgesic, sedative, antipsychotic, and neuromuscular blocker use in Canadian intensive care units: a prospective, multicentre, observational study

Mehta, S.

Can J Anaesth. 2014 Jul;61(7):619-30

Predictors of physical restraint use in Canadian intensive care units

Mehta, S.

Crit Care. 2014 Mar 24;18(2):R46

Scale and pattern of atrophy in the chronic stages of moderate-severe TBI

Mikulis, D.J.
Green, R.E.A.

Front Hum Neurosci. 2014 Mar 31;8:67

Moderate-severe traumatic brain injury causes delayed loss of white matter integrity: evidence of fornix deterioration in the chronic stage of injury

Mikulis, D.
Green, R.

Brain Inj. 2013; 27(12):1415-22

Disruptions of functional connectivity in the default mode network of comatose patients

Mirsattari, S.M.

Neurology. 2012 Jan 17;78(3):175-81

Association between gait variability and brain ventricle attributes: a brain mapping study

Montero-Odasso, M.

Exp Gerontol. 2014 Sep;57:256-63

Use of near infrared spectroscopy to detect impaired tissue oxygen saturation in patients with complex regional pain syndrome type 1

Murkin, J.M.

Can J Anaesth. 2014 Jun;61(6):563-70

The use of an online three-dimensional model improves performance in ultrasound scanning of the spine: a randomized trial

Niazi, A.U.

Can J Anaesth. 2013 May;60(5):458-64

Effect of insulin sensitivity on corticolimbic responses to food picture in women with polycystic ovary syndrome

Palerme, S.
Van Vugt, D.A.

Obesity (Silver Spring). 2013 Jun;21(6):1215-22

Imaging-based diagnosis of autosomal dominant polycystic kidney disease

Pei, Y.

J Am Soc Nephrol. 2014 Jul 29. [Epub ahead of print]

Real-time polymerase chain reaction for microbiological diagnosis of parapneumonic effusions in Canadian children

Pernica, J.M.
Slinger, R.

Can J Infect Dis Med Microbiol. 2014 May; 25(3):151-4

The molecular phenotype of endocapillary proliferation: novel therapeutic targets for IgA nephropathy

Reich, H.N.
Hertzenberg, A.M.

PLoS One. 2014 Aug 18;9(8):e103413

CASQ1 gene is an unlikely candidate for malignant hyperthermia susceptibility in the North American population

Riazi, S.

Anesthesiology. 2013 Feb;118(2):344-9

Cavernous venous malformations of the orbit (so-called cavernous haemangioma): a comprehensive evaluation of their clinical, imaging and histologic nature

Rootman, D.B.
Yucel, Y.H.

Br J Ophthalmol. 2014 Jul;98(7):880-8

Contamination of Canadian private drinking water sources with antimicrobial resistant Escherichia coli

Salvadori, M.I.

Water Res. 2013 Jun 1;47(9):3026-36

Maternal organ donation and acute injuries in surviving children

Scales, D.C.

J Crit Care. 2014 Dec;29(6):923-9

Association between arterial catheter use and hospital mortality in intensive care units

Scales, D.C.

JAMA Intern Med. 2014 Nov 1;174(11):1746-54

Development of a hands-free pointer for instruction during minimally invasive surgery

Schlachta, C.M.

IEEE RAS/EMBS International Conference June 2012

The WHaSP: a wireless hands-free surgical pointer for minimally invasive surgery

Schlachta, C.M.

IEEE/ASME Transactions on Mechatronics, Vol 17, No 3, June 2012

Effect of oximetry on hospitalization in bronchiolitis: a randomized clinical trial

Schuh, S.

JAMA. 2014 Aug 20;312(7):712-8

Utilization of Diabetes Education Centres in Ontario by people without diabetes

Shah, B.R.

Can J Diabetes. 2014 Jun;38(3):186-90

Diabetes education through group classes leads to better care and outcomes than individual counselling in adults: a population-based cohort study

Shah, B.R.

Can J Public Health. 2014 May 9; 105(3):e192-7

Classical HLA-DRB1 and DPB1 alleles account for HLA associations with primary biliary cirrhosis

Siminovitch, K.A.

Genes Immun. 2012 Sep;13(6):461-8

Last wills and testaments in a large sample of suicide notes: implications for testamentary capacity

Sinyor, M.
Schaffer, A.

Br J Psychiatry. 2015 Jan;206(1):72-6

Suicide in bipolar disorder: characteristics and subgroups

Sinyor, M.
Schaffer, A.

Bipolar Disord. 2014 Nov;16(7):732-40

Medications without a patient: potential lethal implications of pharmaceuticals left behind

Sinyor, M.
Schaffer, A.

Crisis. 2014 Jan 1;35(4):283-5

Characterizing suicide in Toronto: an observational study and cluster analysis

Sinyor, M.
Schaffer, A.

Can J Psychiatry. 2014 Jan;59(1):26-33

Comparison of clinical and biochemical markers of dehydration with the clinical dehydration scale in children: a case comparison trial

Tam, R.K.

BMC Pediatr. 2014 Jun 16;14:149

Impact of acute stress on resident performance during simulated resuscitation episodes: a prospective randomized cross-over study

Tarshis, J.
Piquette, D.

Teach Learn Med. 2014;26(1):9-16

Outcomes in presyncope patients: a prospective cohort study

Thiruganasambandamoorthy, V.
Stiell, I.G.

Ann Emerg Med. 2014 Aug 30 [Epub ahead of print]

Risk stratification of adult emergency department syncope patients to predict short-term serious outcomes after discharge (RiSEDS) study

Thiruganasambandamoorthy, V.
Stiell, I.G.

BMC Emerg Med. 2014 Mar 14;14:8

Perioperative cardiovascular system failure in South Asians undergoing cardiopulmonary bypass is associated with prolonged inflammation and increased Toll-like receptor signaling in inflammatory monocytes

Trop, S.
Verma, S.

J Surg Res. 2014 Mar;187(1):43-52

Glucose-induced inhibition of the appetitive brain response to visual food cues in polycystic ovary syndrome patients

Van Vugt, D.A.

Brain Res. 2014 Apr 16;1558:44-56

The association between renal replacement therapy modality and long-term outcomes among critically ill adults with acute kidney injury: a retrospective cohort study

Wald, R.

Crit Care Med. 2014 Apr;42(4):868-77

Changes in quality of life after epilepsy surgery: the role of reprioritization response shift

Wiebe, S.

Epilepsia. 2014 Sep;55(9):1331-8

Autophagy gene fingerprint in human ischemia and reperfusion

Yanagawa, B.
Verma, S.

J Thorac Cardiovasc Surg. 2014 Mar;147(3):1065-1072.e1